Rutter,+Kyle

= Ibuprofen =

Andrew RM Dunlop, with colleagues Stewart Adams, John Nicholson, Vonleigh Simmons, Jeff Wilson and Colin Burrows, at the Boots Group fist discover this drug in 1969. Dr. Adams won the OBE, Officer of the Brittish Empire, which is two steps below knight. Boots won Queen's Award for Technical Acheivement It became available over the counter in the USA in 1974 under the brand name Advil.. It is in the same medical class as Aspirin and commonly used for the same treatments, but ibuprofen increases the risk of heart attacks The FDA has been testing it for many years and it has earned a good reputation world wide
 * History and Background **

Ibuprofen is an over the counter anti-inflammatory drug thats most common use is to help with swollen joints and pain associated with arthritis It can also help with a fevor or can help with other types of pain. It has many possible side effects, but almost all are a varying level of stomach problems Also harmful to babies if taken by the mother when pregnant, or when taken by kids under four Ibuprofen lysine is a mosr souluble for of ibuprofen because it contains Na and can be given through IV May be helpful for Alzheimer's or Parkinson's
 * Uses: **

Fun Facts: First used by the creator to help with a hangover There are almost 90 ibuprofen brands Autopsis can detect it as a poisin leading to investigations of murder Legal dosage in canada is double of the USA Japan sells ibuprofen creams for acne People can have reactions to Advil but not the liquide gels Synthesis: The original synthesis method was the following six steps:

BHC created a easier three step method in 1997 that won the 1997 Presidential Green Chemestry Award. That method is as follows:

**Chemical Properties:**
 * Colorless, crystalline solid
 * Melting Point: 76oC
 * pKa= 4.91
 * Vary soluble in alcohol
 * 206.26 g/mol
 * Vapor Pressure 4.74x105 mmHg

Child Danger! It looks a lot like candy which makes it a danger if kids find it in the home

[|http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3672#x27] [|http://en.wikipedia.org/wiki/Ibuprofen#History]